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Cell Disrupter Selection Table (click for image and more.)

  Animal Tissue Plant Tissue Yeast and Fungi Bacteria Disrupt Timeb Relative Costc Requires Cooling? Requires Prechop? Scale-up Available?

u-MiniBeadbeater,

MiniBeadbeater-1

MiniBeadbeater-16

MiniBeadbeater-25

Mini-Beadbeater-96

+++ +++ ++++ ++++ 3 2 or 3 Yes Yes Yes
BeadBeater -
-
++++

++++

3 2 Yes No Yes

Tissue-Tearor

BioHomogenizer

+++ ++ - <1 2 No Yes Yes
Hamilton-Beach Blenders ++ ++ 1 or 2 2 No No Yes

Cryo-Cup
Mortar & Pestle

+++ +++ 1 1 No Yes No
Tissue Grindera +++ ++ 5 2 No Yes No

MicroMincera

Tissue Pressa

++ + 1 1 or 2 No No No

BioPulverizera

MicroCryoCrushera

++ ++ 0.1 2 No No No

Table Key:

(a) Fragments tissue but does not usually disrupt cells. Often used as a preliminary step.
(b) Typical minutes for 90 percent cell disruption.
(c) Purchase price range:

  1. 1.  $10 - $100
  2. 2.  $100 - $1000
  3. 3.  $1000 and up