SoniBeast - Small Sample Cell Disruptor

  • Incredibly Fast
  • 1 to 12 Sample Capacity
  • Simple One Button Operation

The NEW SoniBeast™ high energy bead-mill cell disruptor completely disrupts small samples of tissue or cells in seconds rather than minutes. It holds up to twelve 0.6 ml PCR microtubes each containing 1-100 mg of sample, or six 2 ml microvials each containing 10-400 mg sample.

Other applications include fine grinding of small quanties of non-biological materials (eg., nanoparticles, catalysts, magnetic media, pigments).

A sample pack of 0.6 ml locking PCR tubes is included with the SoniBeast.  Please order Beads and additional Vials separately.

We're really excited about this amazing new cell disrupter.  It's the biggest improvement in bead-mill cell disrupter design since BioSpec Products invented the Minibeadbeater in 1984.

Our Price : $0.00

The SoniBeast™* cell disrupter homogenizes both microorganisms and plant and animal tissue using the smashing action of colliding ceramic beads (commonly called beadbeating). It departs from contemporary beadbeater machines by oscillating microtubes at a rate of 20,000 oscl/min...some 5 to 50 times faster than currently available beadbeating machines.

As expected, cell disruption occurs much faster when beads inside the tubes are moving at extraordinarily high rates.  Disruption is completed in a few seconds rather than minutes.  Faster disruption times favor higher quality and yields of nucleic acids and proteins because all cells in a tissue sample reach the protection of the extraction media much quicker.  The operation of SoniBeast cell disrupter has also been simplified compared to conventional beadbeaters.  The machine is operated by the push of a single button.  No required manual clamping of tubes or vials onto the machine is required and the physical location of vials remain unchanged from the starting point.  Thus, the SoniBeast is the first high-efficiency bead-mill cell disrupter offering compatibility with robotic systems.

The SoniBeast's tray capacity is one to twelve 0.6 ml PCR microtubes, each containing up to 100 mg of sample.  Closer to the axis of the machine is an inner ring having six positiions that holds larger 1.5 or 2 ml microvials capable of processing up to 400 mg of sample.  Beadbeating rates in the inner ring are lower and mimic that of conventional commercial beadbeaters, thus offering compatibility with earlier published protocols using conventional bead-mill cell disrupters.

*Patent pending

  • Processes one to twelve 0.6 ml locking-cap PCR tubes each holding 1-100 mg (wet weight) of tissue or cells at ultra-high shaking energy or one to six 2 ml screw-cap microvials each holding 10-400 mg (wet weight) tissue or cells at conventional beadbeater shaking energy.  Tubes are typiclly filled 1/2 full of appropriate sized grinding beads.
  • Motor Specifications: 110-120 V~AC, 1.6A, 21000 rpm [Battery poweded and 230 V~AC corded versions soon to be available..please enquire].
  • Manual pulse or timed operation (0.5, 2, 5, 10, 20, 40, and 60 sec with auto-reset) with the push of a single button.
  • Footprint: 5" wide x 16" deep.  Seven inches high. Weight 11 pounds
  • Two year Warranty

What's different about this beadbeater?

The SoniBeast departs from the traditional back-and-forth shaking motion of bead mill-type cell disrupters. Rather, vials are vortexed at an  extrordinarly high speed of 20,000 oscillations/minuteMixing and grinding energy is many times higher than conventional bead beaters or vortexers.  Using 0.6 ml PCR tubes, 1 to 100 milligrams of tissue or cells can be lysed in in seconds rather than minutes.

The SoniBeast also can also accomodate up to six conventional 1.5 and 2 ml microvials.  Samples in these larger microvials are lysed under milder grinding conditions which emulate previously published beadbeating protocols.

One to twelve 0.6 ml microtubes are inserted into a circular tube holder - the plate.  Importantly, and unlike all other beadbeaters, no manual clamping of tubes is required.  After selecting aan auto-reseting run time (typically 5-20 seconds) the SoniBeast is operated with the touch of a single button.  When the machine comes to a stop, the position of tubes and vials are in their exact starting position.  This spacial reproducability, plus the absence of  vial clamping, provides synergy with robotic laboratory methodology.

The bottom line?  Quicker, Simpler, Less Consumables, Smaller Footprint.

For detailed operating instructions see

EVEN SMALLER SAMPLES  A prime goal in developing the SONIBEAST was the ability to disruption of VERY small tissue samples - from milligram down to a few cells.  While the current SONIBEAST has a plate that holds 0.6 ml microtubes, it is easy to convet the SONIBEAST to hold smaller 0.2 ml tubes.