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800.617.3363 or 918.336.3363

Homogenizers & Cell Disrupters - A Selection Table

Proteins and nucleic acids are most often recovered from cells and tissue in a laboratory setting using mechanical methods.  Several factors come into play when choosing the best the method for your application.  They include cell or tissue type,  sample size, desired sample through-put, efficiency and speed of disruption, disruption reproducibility, sample containment, disruptor clean up and disruptor maintence.  Our tech guys can help you make the right choice: Phone 800-617-3363 or e-mail https://www.biospec.com/contact/support.  For a quick scan on what each of our homogenizers offer go to https://biospec.com/cell-disrupter-selection-table

1 Liter Hamilton Beach Blender

1 Liter Hamilton Beach Blender

Hamilton Beach is the worlds largest manufacturer of commercial grade blenders. The model 909 comes with a one liter stainless steel container and can handle the toughest job required from a blade blender.

Cat. No. 909, 115 volt model
Cat. No. 909EUR, 230 volt model

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BeadBeater

BeadBeater

The BeadBeater is the ultimate laboratory-scale homogenizer for disrupting aqueous suspensions of yeast, fungi or bacteria.  Complete cell lysis of 10-80 g (wet weight) of cells is achieved in about three minutes of operation.

The BeadBeater comes complete with a 350 ml polycarbonate chamber, rotor assembly, motor base, ice-water cooling jacket, and your choice of one pound of glass beads...

Select the catalog number ending in...

-101 for 0.1 mm glass beads

-105 for 0.5 mm glass beads

-110 for 1.0 mm glass beads

Also, if the BeadBeater is to be used in countries with a 220-240 volt power supply, please select the catalog number containing "EUR."

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BioHomogenizer

BioHomogenizer

The BioHomogenizer is a rotor-stator type tissue homogenizer designed to rapidly homogenize, disperse, and emulsify biological samples in aqueous media from 1 to 1000 ml.  The BioHomogenizer includes both the motor and probe.

Cat. No. 1281, BioHomogenizer for 1-200ml samples, complete with 1.4 cm probe
Cat. No. 1281EUR, 230 volt version of No. 1281
Cat. No. 1285, BioHomogenizer for 100-2000ml samples, complete with 2.5 cm probe
Cat. No. 1285EUR, 230 volt version of No. 1285

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BioMixer

BioMixer

A low cost, versatile high-speed mixer and blender.  Perfect for blade blending in open beakers, jars and bowls. Swiss-made.

Cat. No. 10810,  BioMixer, 115 volt Includes three mixing attachments, grinding mill, and plastic stand.
Cat. No. 10810EUR, BioMixer, 230 volt Includes three mixing attachments, grinding mill, and plastic stand.

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BioSqueezer

BioSqueezer

The BioSqueezer is used to "snap-freeze" (quickly freeze) 10-100 mg of soft animal and human tissue.  Fresh tissue is compressed into a thin disc about the size of a small coin under pressure from a stainless steel clamp head that has been pre-cooled in liquid nitrogen or dry ice.   Freezing occurs in a few milliseconds, thus offering a snapshot of metabolic events in the cells.  The hard frozen disc is easily fragmented by hand or ground without thawing in a Cryo-Cup mortar and pestle for subsequent rapid extraction of labile nucleic acids, proteins and intracellular metabolite products.

 

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Cryo-Cup Grinder

Cryo-Cup Grinder

The Cryo-Cup Grinder is a mortar and pestle specifically designed to pulverize and powder plant and animal tissue samples at liquid nitrogen temperatures.  It gives superior results compared to conventional ceramic mortar-pestles.

Cat. No. 206, Cryo-cup Grinder, complete, includes two different size polypropylene pestle balls. See below for extra cups (mortars) and pestle balls.

Cat. No. 206C, Extra s.s. mortar with insulated cup. (Pestle not included)
Cat. No. 206PP138, Polypropylene ball, 1  3/8 inch dia.
Cat. No. 206PP178, Polypropylene ball, 1  7/8 inch dia.
Cat. No. 206SS138, Stainless steel ball, 1  3/8 inch dia.
Cat. No. 206SS178, Stainless steel ball, 1  7/8 inch dia.

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CryogenicTissueGrinder

CryogenicTissueGrinder

The CryogenicTissueGrinder is a high-speed blade mill that grinds 1-10 grams of microbial, plant, animal and human tissue having high water content (~70%) to a fine powder in the presence of excess dry-ice. At solid CO2 temperatures, the hard and brittle sample is powdered in seconds.  Pulverizing tissue at very low temperature stabilizes intercellular biochemicals and prepares the tissue for rapid extraction in an appropriate liquid media.

Cat. No. CTG111, 120 volts

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Mini-Beadbeater-16

Mini-Beadbeater-16

The Mini-Beadbeater-16 is a high-energy cell disrupter designed to handle four to sixteen samples at a time.

Cat. No. 607, Mini-BeadBeater-16, 115 volt
Cat. No. 607EUR, Mini-Beadbeater-16, 220-240 volt

Note for European buyers:

See the Mini-BeadBeater 24 if CE certification is required.

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Mini-Beadbeater-24

Mini-Beadbeater-24

The Mini-Beadbeater-24 disrupts up to 24 microbial or tissue samples with better than 95 percent efficiency. Cells are disrupted quickly and safely in the sealed system. The apparatus is easy to clean, has a small footprint and is essentially maintenance free. Compared to the Minibeadbeater-16, the Mini-24 adds advanced electronics for enhanced motor function, variable speeds of 2400-3800 rpm and a 30% increase in microvial capacity.

Cat. No. 112011, Mini-BeadBeater-24, 115 volt
Cat. No. 112011EUR, Mini-Beadbeater-24, 230 volt

European buyers! The Mini-Beadbeater-24 is CE certified.

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Mini-Beadbeater-96

Mini-Beadbeater-96

The Mini-Beadbeater-96 is high-energy, high-throughput cell disrupter.  It can process one 2 ml deep well micro plate (96 samples), two 1 ml deep well microplates (192 samples) or, using a included 45 capacity polypropylene microvial rack, 0.6, 1.5 or 2 ml microvials.  In a busy day thousands of samples can be processed.

Cat. No. 1001, Mini-Beadbeater-96, 115 volt. 

Cat. No. 1001EUR, Mini-Beadbeater-96, 230 volt.

Beads and vials vary with the application and should be ordered separately.  For selecting Beads and Vials see their links in Browse box in the left margin.

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Mini-Beadbeater-Plus

Mini-Beadbeater-Plus

The Mini-Beadbeater-Plus™ is our upgraded version of the venerable Mini-BeadBeater-1.  It is a high-energy single-vial bead-mill used to disrupt cells of biological samples.  The Mini-BeadBeater-Plus can also grind samples of friable minerals or organic materials.  Up tp 0.4 g of material is placed in a 2 ml microvial containing glass-, ceramic- or steel beads and "beadbeat" for 10 to 99 seconds. Typically, in a busy afternoon, about 20 samples can be processed for analysis.  For much larger sample through-put, see our multi-vial MBB-16, MBB-24 and MBB-96 .  Protocols developed using the Mini-BeadBeater-PLUS transfer to other Mini-BeadBeater models .

Cat. No. 1018, Mini-BeadBeater-Plus, 110/220 volt

Note:  Required vials and beads vary with the particular sample being disrupted and should be purchased separately.  For guidance on selecting Beads and Vials see the links in Browse box in the left margin of this web page.  If you would like to discuss your application with a technical expert e-mail us or give us a call at 918-336-3363.

 

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Onyx Mortar & Pestle

Onyx Mortar & Pestle

A beautiful, hand-made mortar & pestle sculptured out of onyx stone.

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Porcelain Mortar & Pestle

Porcelain Mortar & Pestle

Low profile porcelain mortar and pestle.

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Semi-Continuous Tissue Disperser

Semi-Continuous Tissue Disperser

A top-of-the-line domestic waste disposer modified to sit on a lab bench.  Close loop plumbing has been added to recycle the contents.  The Semi-Continous Tissue Disperser delivers a high quality homogenate of almost any plant or animal material.  Kilogram quantities of material can be processed in minutes using a batch-wise or in a semi-continuous mode.  Can be operated at room temperature or a cold room.

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SoniBeast - Small Sample Cell Disruptor

SoniBeast - Small Sample Cell Disruptor

  • Extremely Fast Cell Lysis...<20 sec
  • Perfect for Small Samples
  • 12 Vial Capacity
  • Simple One Button Operation

The NEW SoniBeast™ high energy bead-mill cell disruptor completely disrupts small samples of tissue or cells in seconds rather than minutes. It holds up to twelve 0.6 ml PCR microtubes each containing 1-100 mg of sample, or six 2 ml microvials each containing 10-400 mg sample.  The SoniBeast is designed for wet milling in water-based media. Common applications are the isolation of intracellular protein and nucleic acids.

A sample pack of 0.6 ml locking cap PCR tubes is included with the SoniBeast.  Beads and additional Vials should be ordered separately.

We're really excited about this amazing new cell disrupter.  It's the biggest improvement in bead-mill cell disrupter design since the beadbeater cell disruptor was introduced 30+ years ago.

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SpiralPestle and Tube Grinder

SpiralPestle and Tube Grinder

The NEW SpiralPestle™ and 1.5 ml Microtube grinder is an significant improvement over conventional smooth-walled polypropylene pestle and tube combinations.  It is used to homogenize culture cells and small samples (<100 mg wet weight) of soft tissue such as liver, brain, and muscle.  It is also routinely used to disperse centrifugal pellets, precipitates, and other solids.

Cat. No. 1017, SpiralPestles™ and 1.5 ml microvials (100 count) and sample of Spiral Grinding Beads.

Cat. No. 1017MC, Above Cat. No. 1017 plus a BioVortexer™ motor (Cat. No. 1083).

Cat. No. 1017GB, SpiralPestle Grinding Beads.  Glass beads for pestle and microvial grinders, 50 cc bottle with pour spout.

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Stainless Steel TissueGrinder

Stainless Steel TissueGrinder

All stainless steel Potter-Elvehjem style tubular mortar and pestle.  Superb temperature control during use, shatter-free, easy to clean.

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Tissue-Tearor

Tissue-Tearor

The Tissue-Tearor is a rotor/stator type tissue homogenizer which can rapidly homogenize, disrupt, and emulsify samples in 0.5 - 1000 ml of liquid.  Complete homogenization of tissues (muscle, liver, breast tissue, etc.) is usually achieved in ten to thirty seconds. Little, if any, heat is produced during the process.

If you need a 230 volt unit, please select models that end in EUR.  When ordering select one of our four different probe sizes - 04, 07, XL, and 14. Unlike most competitive Brands of rotor-stator homogenizer, THE TISSUE-TEAROR COMES COMPLETE WITH BOTH THE HIGH-SPEED MOTOR AND ONE STAINLESS STEEL PROBE OF YOUR CHOICE.  See chart below for probe selection guidance. Additional probes are available.  All are interchangeable with the TT motor unit.  A cord-less variety of the TissueTearor is also available with model numbers ending in CL.
 

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